盖文贤

硕士生导师

Email: gaiwenxian@163.com; gaiwenxian@ldu.edu.cn

研究方向

功能基因组学及分子育种

个人简介

2021年于西北农林科技大学获得博士学位，随后在华中农业大学进行博士后研究，2024年，正式加入鲁东大学。主要从事番茄、苹果的基因组学与分子育种研究，致力于通过基因组学、分子生物学和遗传学等多学科手段，探索重要农艺性状的遗传变异及其调控机制，解析其生物学功能及其在遗传改良中的应用。研究成果以第一作者/通讯作者发表在Horticulture Research等国际主流学术期刊；受邀担任Horticulture Plant Journal等多个期刊审稿人。

科研项目

1. 湖北省自然科学基金青年项目，番茄柠檬酸新遗传位点qTFC2.4和qTFC10.2的候选基因鉴定及 育种应用，2024/03-2026/03，主持

发表论文

[1] Gai W X, Yuan L D, Yang F, Ahiakpa J K, Li F M, Ge P F, Zhang X Y, Tao J B, Wang F, Yang Y, Zhang Y Y.Genome-wide variants and optimal allelic combinations for citric acid in tomato[J].Horticulture Research,2024, 11 (5): uhae070.

[2] Gai W, Yang F, Yuan L, Haq S U, Wang Y, Wang Y, Shang L, Li F, Ge P, Dong H, Tao J, Wang F, Zhang X, Zhang Y.Multiple-model GWAS identifies optimal allelic combinations of quantitative trait loci for malic acid in tomato[J].Horticulture Research,2023, 10 (4): uhad021.

[3] Gai W X, Yang F, Ali M, Ahmad A, Gong Z H.Pepper heat shock transcription factor A1d contributes to seed thermotolerance and germination vigor[J].Scientia Horticulturae,2023, 311: 111786.

[4] Gai W X, Ma X, Qiao Y M, Shi B H, Ul Haq S, Li Q H, Wei A M, Liu K K, Gong Z H.Characterization of the bZIP transcription factor family in pepper (Capsicum annuum L.): CabZIP25 positively modulates the salt tolerance[J].Front Plant Sci,2020, 11: 139.

[5] Gai W X, Ma X, Li Y, Xiao J J, Khan A, Li Q H, Gong Z H.CaHsfA1d improves plant thermotolerance via regulating the expression of stress- and antioxidant-related genes[J].International Journal of Molecular Sciences,2020, 21 (21): 8374.

[6] Yang F, Han S X, Zhang Y X, Chen X X, Gai W X, Zhao T.Phylogenomic Analysis and Functional Characterization of the APETALA2/Ethylene-Responsive Factor Transcription Factor Across Solanaceae[J].International Journal of Molecular Sciences,2024, 25 (20).

[7] Xiao J J, Zhang R X, Khan A, Ul Haq S, Gai W X, Gong Z H.CaFtsH06, A Novel Filamentous Thermosensitive Protease Gene, Is Involved in Heat, Salt, and Drought Stress Tolerance of Pepper (Capsicum annuum L.)[J].International Journal of Molecular Sciences,2021, 22 (13).

[8] Wang Y, Shi C, Ge P, Li F, Zhu L, Wang Y, Tao J, Zhang X, Dong H, Gai W, Wang F, Ye Z, Grierson D, Xu W, Zhang Y.A 21-bp InDel in the promoter of STP1 selected during tomato improvement accounts for soluble solid content in fruits[J].Horticulture Research,2023.

[9] Ul Haq S, Khan A, Ali M, Khattak A M, Gai W X, Zhang H X, Wei A M, Gong Z H.Heat Shock Proteins: Dynamic Biomolecules to Counter Plant Biotic and Abiotic Stresses[J].Int J Mol Sci,2019, 20 (21): 5321.

[10] Ul Haq S, Khan A, Ali M, Gai W X, Zhang H X, Yu Q H, Yang S B, Wei A M, Gong Z H.Knockdown of CaHSP60-6 confers enhanced sensitivity to heat stress in pepper (Capsicum annuum L.)[J].Planta,2019, 250 (6): 2127-2145.

[11] Tamim S A, Li F, Wang Y, Shang L, Zhang X, Tao J, Wang Y, Gai W, Dong H, Ahiakpa J K, Mumtaz M A, Zhang Y.Effect of shading on ascorbic acid accumulation and biosynthetic gene expression during tomato fruit development and ripening[J].Vegetable Research,2022, 2 (1): 1-8.

[12] Shang L L, Tao J B, Song J W, Wang Y R, Zhang X Y, Ge P F, Li F M, Dong H Q, Gai W X, Grierson D, Ye Z B, Zhang Y Y.CRISPR/Cas9-mediated mutations of FANTASTIC FOUR gene family for creating early flowering mutants in tomato[J].Plant Biotechnol J,2024, 22 (3): 774-784.

[13] Mumtaz M A, Wang Y, Li F M, Shang L L, Wang Y R, Zhang X Y, Tao J B, Gai W X, Dong H Q, Ahiakpa J K, Zhang Y Y.Hindered tomato reproductive development by altered brassinosteroid sensitivity1 mutant[J].Plant Growth Regulation,2022, 96 (3): 473-481.

[14] Ma X, Li Y, Gai W-X, Li C, Gong Z-H.The CaCIPK3 gene positively regulates drought tolerance in pepper[J].Horticulture Research,2021, 8 (1): 216.

[15] Ma X, Gai W X, Qiao Y M, Ali M, Wei A M, Luo D X, Li Q H, Gong Z H.Identification of CBL and CIPK gene families and functional characterization of CaCIPK1 under Phytophthora capsici in pepper (Capsicum annuum L.)[J].BMC Genomics,2019, 20 (1): 775.

[16] Ma X, Gai W X, Li Y, Yu Y N, Ali M, Gong Z H.The CBL-interacting protein kinase CaCIPK13 positively regulates defence mechanisms against cold stress in pepper[J].J Exp Bot,2022, 73 (5): 1655-1667.

[17] Li Y, Ma X, Gai W X, Xiao L D, Gong Z H.First Report of Colletotrichum gloeosporioides Causing Anthracnose on Pepper in Shaanxi Province, China[J].Plant Dis,2021, 105 (8): 2242-2242.

[18] Li Q H, Yang S P, Yu Y N, Khan A, Feng P L, Ali M, Shao D K, Wang Y Y, Zhang R X, Gai W X, Han R, Ma X, Hou Q G, Gong Z H.Comprehensive transcriptome-based characterization of differentially expressed genes involved in carotenoid biosynthesis of different ripening stages of Capsicum[J].Scientia Horticulturae,2021, 288.

[19] Haq S U, Khan A, Ali M, Gai W X, Zhang H X, Yu Q H, Yang S B, Wei A M, Gong Z H.Knockdown of CaHSP60-6 confers enhanced sensitivity to heat stress in pepper (Capsicum annuum L.)[J].Planta,2019, 250 (6): 2127-2145.

[20] Feng X H, Zhang H X, Ali M, Gai W X, Cheng G X, Yu Q H, Yang S B, Li X X, Gong Z H.A small heat shock protein CaHsp25.9 positively regulates heat, salt, and drought stress tolerance in pepper (Capsicum annuum L.)[J].Plant Physiol Biochem,2019, 142: 151-162.

[21] Ali M, Luo D X, Khan A, Haq S U, Gai W X, Zhang H X, Cheng G X, Muhammad I, Gong Z H.Classification and Genome-Wide Analysis of Chitin-Binding Proteins Gene Family in Pepper (Capsicum annuum L.) and Transcriptional Regulation to Phytophthora capsici, Abiotic Stresses and Hormonal Applications[J].Int J Mol Sci,2018, 19 (8).

[22] Ali M, Gai W X, Khattak A M, Khan A, Haq S U, Ma X, Wei A M, Muhammad I, Jan I, Gong Z H.Knockdown of the chitin-binding protein family gene CaChiIV1 increased sensitivity to Phytophthora capsici and drought stress in pepper plants[J].Mol Genet Genomics,2019, 294 (5): 1311-1326.

[23]盖文贤, 陈卫芳, 王莹; 李方曼, 张星雨, 陶金宝, 尚乐乐, 王亚茹, 董海强, 张余洋. 番茄抗坏血酸含量QTL定位及候选基因PPO功能分析. 园艺学报, 2021, 48(S1): 2667.

[24]盖文贤, 李芳东, 张福兴, 孙庆田.果树对盐胁迫的响应及缓解机制研究进展[J].北方园艺,2015(09):182-186.